Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488242 | 0.86 | MAPT (0.53) | POLBCYP2C9RECQLALDH1A1MAPT | |
| SCHEMBL7490926 | 0.85 | CYP2C9 (0.42) | POLBCYP2C9RECQLALDH1A1MAPT | |
| SCHEMBL7493393 | 0.85 | SLC10A2 (0.47) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL7494813 | 0.85 | MAPT (0.44) | POLBCYP2C9RECQLALDH1A1MAPT | |
| SCHEMBL7490054 | 0.84 | PRKCI (0.45) | POLBCYP2C9ALDH1A1MAPTHPGD | |
| SCHEMBL7490046 | 0.82 | ALDH1A1 (0.35) | POLBCYP2C9ALDH1A1MAPTHPGD | |
| SCHEMBL8806198 | 0.80 | ALDH1A1 (0.44) | POLBCYP2C9RECQLALDH1A1MAPT | |
| Diethylamine SCHEMBL7494820 | 0.79 | CYP2C9 (0.52) | POLBCYP2C9RECQLALDH1A1MAPT | |
| SCHEMBL7485233 | 0.77 | MAPT (0.56) | POLBCYP2C9ALDH1A1MAPTHPGD | |
| SCHEMBL7484252 | 0.75 | MAPT (0.49) | POLBCYP2C9RECQLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5747486-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |