Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495407 | 1.00 | SYK (0.49) | SYKCTSBBACE1PSMB5PSMB1 | |
| SCHEMBL7568028 | 0.84 | SYK (0.55) | SYKCTSBBACE1PSMB5CTSK | |
| SCHEMBL7499769 | 0.84 | CTSK (0.50) | SYKCTSBBACE1CTSKCTSL | |
| SCHEMBL7568024 | 0.84 | SYK (0.55) | SYKCTSBBACE1PSMB5CTSK | |
| SCHEMBL7499786 | 0.84 | CTSK (0.50) | SYKCTSBBACE1CTSKCTSL | |
| SCHEMBL7573918 | 0.80 | SYK (0.52) | SYKCTSBBACE1PSMB5PSMB1 | |
| SCHEMBL2061787 | 0.80 | SYK (0.55) | SYKCTSBPSMB5PSMB1PSMB2 | |
| SCHEMBL187066 | 0.80 | SYK (0.55) | SYKCTSBPSMB5PSMB1PSMB2 | |
| SCHEMBL2062558 | 0.80 | SYK (0.55) | SYKCTSBPSMB5PSMB1PSMB2 | |
| SCHEMBL7575306 | 0.79 | SYK (0.50) | SYKBACE1PSMB5CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |