Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568028 | 0.86 | SYK (0.55) | SYKPSMB5BACE1CTSKCTRB1 | |
| SCHEMBL7568024 | 0.86 | SYK (0.55) | SYKPSMB5BACE1CTSKCTRB1 | |
| SCHEMBL7499769 | 0.84 | CTSK (0.50) | SYKBACE1CTSKALDH1A1CTSL | |
| SCHEMBL7499786 | 0.84 | CTSK (0.50) | SYKBACE1CTSKALDH1A1CTSL | |
| SCHEMBL7573918 | 0.82 | SYK (0.52) | SYKPSMB5BACE1CTSKCTRB1 | |
| SCHEMBL7495407 | 0.79 | SYK (0.49) | SYKPSMB5BACE1CTSKCTSL | |
| SCHEMBL7495397 | 0.79 | SYK (0.49) | SYKPSMB5BACE1CTSKCTSL | |
| SCHEMBL10905437 | 0.75 | SYK (0.53) | SYKPSMB5BACE1CTSKCTRB1 | |
| SCHEMBL10905434 | 0.75 | SYK (0.53) | SYKPSMB5BACE1CTSKCTRB1 | |
| SCHEMBL10705256 | 0.75 | SYK (0.46) | SYKBACE1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |