Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499769 | 1.00 | CTSK (0.50) | CTSKKYNUSYKALDH1A1ALOX15 | |
| SCHEMBL7568028 | 0.85 | SYK (0.55) | CTSKSYKBACE1CTSSCTSL | |
| SCHEMBL7568024 | 0.85 | SYK (0.55) | CTSKSYKBACE1CTSSCTSL | |
| SCHEMBL20364471 | 0.84 | KYNU (0.49) | CTSKKYNUSYKALDH1A1ALOX15 | |
| SCHEMBL7495407 | 0.84 | SYK (0.49) | CTSKSYKBACE1CTSSCTSL | |
| SCHEMBL7495397 | 0.84 | SYK (0.49) | CTSKSYKBACE1CTSSCTSL | |
| SCHEMBL7575306 | 0.84 | SYK (0.50) | CTSKSYKALDH1A1BACE1CTSS | |
| SCHEMBL15122801 | 0.83 | KYNU (0.48) | CTSKKYNUSYKALDH1A1ALOX15 | |
| SCHEMBL18426810 | 0.83 | KYNU (0.48) | CTSKKYNUSYKALDH1A1ALOX15 | |
| SCHEMBL15122799 | 0.83 | KYNU (0.48) | CTSKKYNUSYKALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |