Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496095 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HPGDMCL1TSHRMAPK10 | |
| SCHEMBL11422547 | 0.81 | TSHR (0.49) | ALDH1A1HPGDTSHRMAPK10LMNA | |
| SCHEMBL7493234 | 0.81 | HDAC3 (0.53) | ALDH1A1TSHRMAPK10MMEHDAC3 | |
| SCHEMBL7493230 | 0.81 | HDAC3 (0.53) | ALDH1A1TSHRMAPK10MMEHDAC3 | |
| SCHEMBL7491261 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDMCL1TSHRMAPK10 | |
| SCHEMBL4118521 | 0.77 | HDAC8 (0.41) | ALDH1A1HPGDTSHRLMNAHDAC3 | |
| SCHEMBL5238435 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDTSHRMAPK10MEN1 | |
| SCHEMBL5238423 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDTSHRMAPK10MEN1 | |
| SCHEMBL5238428 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HPGDTSHRMAPK10MEN1 | |
| SCHEMBL11419903 | 0.74 | TSHR (0.41) | ALDH1A1TSHRMAPK10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |