Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PER2 | O15055 | 2/20 | 0.41 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469734 | 0.82 | POLB (0.51) | POLBNPC1RAB9A | |
| SCHEMBL4664868 | 0.75 | SMN1; SMN2 (0.51) | SLC6A2SLC6A3 | |
| SCHEMBL7820778 | 0.74 | ALDH1A1 (0.48) | POLB | |
| SCHEMBL11035491 | 0.73 | LMNA (0.54) | POLBNPC1RAB9A | |
| SCHEMBL5092543 | 0.72 | CD274 (0.56) | POLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5443083 | 0.70 | L3MBTL1 (0.52) | NPC1RAB9A | |
| SCHEMBL13096997 | 0.69 | POLB (0.73) | POLBNPC1RAB9A | |
| SCHEMBL20201606 | 0.69 | NPY4R (0.42) | POLBNPC1RAB9A | |
| SCHEMBL2227579 | 0.69 | POLB (0.69) | POLBNPC1RAB9A | |
| SCHEMBL15075237 | 0.69 | POLB (0.69) | POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115702-A4 | SUBSTITUTED NITROGEN AND SULFUR ALICYCLIC COMPOUNDS, INCLUDING METHODS FOR SYNTHESIS THEREOF | MILLENNIUM PHARM INC (US) | 2002-04-17 | — | — | EP | disclosed |
| EP-1115702-A1 | SUBSTITUTED NITROGEN AND SULFUR ALICYCLIC COMPOUNDS, INCLUDING METHODS FOR SYNTHESIS THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000001670-A1 | SUBSTITUTED NITROGEN AND SULFUR ALICYCLIC COMPOUNDS, INCLUDING METHODS FOR SYNTHESIS THEREOF | LEUKOSITE, INC. (US) | 2000-01-13 | — | — | WO | disclosed |