Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARL | Q9H300 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341570 | 0.84 | TLR9 (0.52) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL28933339 | 0.74 | KMT2A (0.61) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL13056396 | 0.74 | TLR9 (0.74) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL6025147 | 0.74 | KMT2A (0.66) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL3361338 | 0.74 | KDM4E (0.48) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL3211086 | 0.74 | KMT2A (0.56) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL28503118 | 0.74 | MGLL (0.61) | MAPK1HPGDTP53KMT2AMAPT | |
| SCHEMBL3786268 | 0.74 | MGLL (0.61) | TP53KMT2AMAPTMEN1RAF1 | |
| SCHEMBL3842955 | 0.72 | HSD17B10 (0.44) | HPGDTP53KMT2AMAPTMEN1 | |
| SCHEMBL1920666 | 0.71 | MAPK1 (0.40) | MAPK1HPGDTP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | claimed |
| CN-1066730-C | Bicyclic amines as insecticides | ZENECA LTD (GB) | 2001-06-06 | — | — | CN | claimed |
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | disclosed |
| US-6207676-B1 | Bicyclic amines | ZENECA LIMITED (GB) | 2001-03-27 | — | — | US | disclosed |