SCHEMBL3786268

SCHEMBL3786268

O=C1CCC(=O)N1c1ccccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.61
ALOX5 P09917 2/20 0.50
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 5/20 0.47
POLB P06746 3/20 0.47
MAPT P10636 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
CASP1 P29466 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
RAF1 P04049 1/20 0.47
MAPK3 P27361 1/20 0.47
MAP3K8 P41279 1/20 0.47
MAP2K1 Q02750 1/20 0.47
TP53 P04637 1/20 0.46
GRM4 Q14833 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6341570 0.84 TLR9 (0.52) KMT2AMEN1POLBMAPTL3MBTL1
SCHEMBL2470770 0.83 RAD51 (0.48) MGLLKMT2AALDH1A1POLBMAPT
SCHEMBL8117328 0.79 MAPT (0.61) MGLLALOX5KMT2AMEN1ALDH1A1
SCHEMBL11425493 0.79 MGLL (0.51) MGLLALOX5KMT2AMEN1ALDH1A1
SCHEMBL9819404 0.79 MGLL (0.47) MGLLALOX5KMT2AMEN1ALDH1A1
SCHEMBL11422039 0.77 MGLL (0.46) MGLLALOX5KMT2AMEN1ALDH1A1
SCHEMBL11133610 0.76 HPGD (0.62) MGLLKMT2AMEN1ALDH1A1POLB
SCHEMBL24034719 0.76 MGLL (0.62) MGLLALOX5KMT2AMEN1ALDH1A1
SCHEMBL58050 0.76 MGLL (1.00) MGLLKMT2AMEN1ALDH1A1POLB
SCHEMBL29376713 0.76 MGLL (1.00) MGLLKMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107573274-A A kind of preparation method of heat-proof modifier N tert-butylmaleimides 蔚林新材料科技股份有限公司 2018-01-12 CN disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 MGLL 1314/4885ALOX5 1128/4885KMT2A 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.