Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341570 | 0.84 | TLR9 (0.52) | KMT2AMEN1L3MBTL1MAPK1TP53 | |
| SCHEMBL9819256 | 0.79 | MEN1 (0.47) | KMT2AMEN1MGLLEPHX2PGR | |
| SCHEMBL7008036 | 0.76 | HPGD (0.62) | KMT2AMEN1MGLLEPHX2PGR | |
| SCHEMBL29510492 | 0.76 | MGLL (1.00) | KMT2AMEN1MGLLPGRALDH1A1 | |
| SCHEMBL3169850 | 0.76 | MGLL (1.00) | KMT2AMEN1MGLLPGRALDH1A1 | |
| SCHEMBL28494976 | 0.75 | KMT2A (0.58) | KMT2AMEN1MGLLEPHX2PGR | |
| SCHEMBL7496597 | 0.74 | MAPK1 (0.41) | KMT2AMEN1L3MBTL1MAPK1TP53 | |
| SCHEMBL3786268 | 0.74 | MGLL (0.61) | KMT2AMEN1MGLLL3MBTL1TP53 | |
| SCHEMBL13056396 | 0.74 | TLR9 (0.74) | KMT2AMEN1MGLLMAPK1TP53 | |
| SCHEMBL6025147 | 0.74 | KMT2A (0.66) | KMT2AMEN1MGLLL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583902-B | Preparation method of alkynyl thioether compound | 江苏医药职业学院 | 2024-02-13 | — | — | CN | disclosed |
| CN-115583902-A | Preparation method of alkynyl thioether compound | 江苏医药职业学院 | 2023-01-10 | — | — | CN | disclosed |