Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444385 | 0.85 | CYP1A2 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL4589939 | 0.85 | CYP1A2 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL8501127 | 0.85 | CYP1A2 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL25755453 | 0.85 | ALDH1A1 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT | |
| SCHEMBL12343942 | 0.81 | ALOX15 (0.38) | ALDH1A1CYP1A2ALOX15GAAMGAM | |
| SCHEMBL20605561 | 0.81 | ALOX15 (0.38) | ALDH1A1CYP1A2ALOX15GAAMGAM | |
| SCHEMBL3141492 | 0.81 | GAA (0.38) | ALDH1A1CYP1A2ALOX15GAAMGAM | |
| Hydrochloric Acid SCHEMBL13276364 | 0.79 | ALOX15 (0.37) | ALDH1A1CYP1A2ALOX15GAAMGAM | |
| Hydrochloric Acid SCHEMBL2789388 | 0.79 | ALOX15 (0.37) | ALDH1A1CYP1A2ALOX15GAAMGAM | |
| SCHEMBL20139837 | 0.78 | CYP2C19 (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929547-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6265404-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-07-24 | — | — | US | disclosed |
| US-6232325-B1 | THROMBOSIS THERAPY | BERLEX LABORATORIES, INC. | 2001-05-15 | — | — | US | disclosed |
| US-6177473-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-01-23 | — | — | US | disclosed |
| US-6008234-A | TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY, INHIBITING HUMAN BLOOD COAGULATION FACTOR XA | BERLEX LABORATORIES, INC. (US) | 1999-12-28 | — | — | US | disclosed |