Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589939 | 1.00 | CYP1A2 (0.37) | CYP1A2GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL8501127 | 1.00 | CYP1A2 (0.37) | CYP1A2GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL7497017 | 0.85 | CYP3A4 (0.41) | CYP1A2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL12343942 | 0.81 | ALOX15 (0.38) | CYP1A2GAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20605561 | 0.81 | ALOX15 (0.38) | CYP1A2GAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3141492 | 0.81 | GAA (0.38) | CYP1A2GAAALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL13276364 | 0.79 | ALOX15 (0.37) | CYP1A2GAAALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL2789388 | 0.79 | ALOX15 (0.37) | CYP1A2GAAALDH1A1KDM4EALOX15 | |
| SCHEMBL22945696 | 0.78 | GAA (0.35) | CYP1A2GAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31462441 | 0.78 | GAA (0.35) | CYP1A2GAAALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138621-A2 | SYNTHESIS OF AMINOCYCLOPENTANE CARBOXYLIC ACIDS | FAUST PHARMACEUTICALS (FR) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008138620-A2 | 1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACIDS DERIVATIVES | FAUST PHARMACEUTICALS (FR) | 2008-11-20 | — | — | WO | disclosed |
| EP-1992637-A1 | 1-Aminocyclopentane-1,3,4- tricarboxylic acids derivatives | Faust Pharmaceuticals (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992610-A1 | New route of synthesis | Faust Pharmaceuticals (FR) | 2008-11-19 | — | — | EP | disclosed |