Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 12/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358790 | 0.79 | HTR6 (0.65) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL21959033 | 0.77 | HTR6 (0.74) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL3644542 | 0.75 | HTR6 (1.00) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL5355112 | 0.73 | HTR6 (0.60) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL1172350 | 0.73 | HTR6 (0.77) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL31211647 | 0.73 | HTR6 (0.77) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL20564256 | 0.73 | HTR6 (0.72) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL27757843 | 0.72 | HTR6 (0.59) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL20561500 | 0.72 | L3MBTL1 (0.73) | L3MBTL1HTR6DRD2CA12CA9 | |
| SCHEMBL5356793 | 0.72 | HTR6 (0.61) | L3MBTL1HTR6DRD2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |