Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 5/20 | 0.43 |
| ▸ | GABRD | O14764 | 5/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.43 |
| ▸ | GABRE | P78334 | 5/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361098 | 0.86 | MAPK1 (0.56) | TDP1L3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL30402493 | 0.86 | MAPK1 (0.56) | TDP1L3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL9901416 | 0.86 | CYP1A2 (0.51) | CYP1A2MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL31680822 | 0.82 | P4HTM (0.41) | TDP1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL362304 | 0.81 | P4HTM (0.58) | CYP1A2TDP1L3MBTL1MAPTKDM4E | |
| SCHEMBL29889518 | 0.80 | CHEK2 (0.48) | MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11372982 | 0.80 | PLA2G4B (0.40) | CYP1A2TDP1L3MBTL1MAPTNPC1 | |
| SCHEMBL2140228 | 0.78 | NPC1 (0.50) | CYP1A2MAPTNPC1RAB9AGABRP | |
| SCHEMBL225619 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1 | |
| SCHEMBL712413 | 0.78 | CYP1A2 (0.50) | CYP1A2TDP1L3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138209-B2 | Substituted picolinamides as MAO-B inhibitors useful for treating obesity | JENRIN DISCOVERY, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20070015734-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015734-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | CYP1A2 25/4885TDP1 1579/4885L3MBTL1 3671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.