Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082635 | 0.92 | TSPO (0.80) | TSPOSMN1; SMN2MAPTTP53 | |
| SCHEMBL7750388 | 0.90 | TSPO (0.56) | TSPOSMN1; SMN2MAPTTP53KDM4E | |
| SCHEMBL600372 | 0.89 | TSPO (0.78) | TSPOSMN1; SMN2MAPTTP53KDM4E | |
| SCHEMBL7497769 | 0.85 | TSPO (0.51) | TSPOSMN1; SMN2MAPTTP53KDM4E | |
| SCHEMBL197375 | 0.83 | TSPO (1.00) | TSPOMAPT | |
| SCHEMBL7499582 | 0.83 | TSPO (0.51) | TSPOSMN1; SMN2MAPTTP53KDM4E | |
| SCHEMBL8958820 | 0.81 | TSPO (0.64) | TSPOKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7492444 | 0.81 | TSPO (0.46) | TSPOSMN1; SMN2MAPTTP53KDM4E | |
| SCHEMBL10042107 | 0.80 | TSPO (0.84) | TSPOSMN1; SMN2MAPTTP53HPGD | |
| SCHEMBL7750398 | 0.78 | TSPO (0.69) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000063-B1 | 4-OXO-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-b]INDOLE-1-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI SYNTHELABO (FR) | 2002-10-23 | — | — | EP | disclosed |
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |