Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497799 | 0.90 | TSPO (0.71) | TSPOKMT2ATSHRHPGDKDM4E | |
| SCHEMBL7497769 | 0.89 | TSPO (0.51) | TSPOPOLBKMT2ATSHRHPGD | |
| SCHEMBL7750398 | 0.88 | TSPO (0.69) | TSPO | |
| SCHEMBL7750505 | 0.88 | TSPO (0.61) | TSPOPOLBKMT2ATSHRHPGD | |
| SCHEMBL7499582 | 0.87 | TSPO (0.51) | TSPOPOLBKMT2ATSHRHPGD | |
| SCHEMBL7492444 | 0.84 | TSPO (0.46) | TSPOPOLBKMT2ATSHRHPGD | |
| SCHEMBL7745876 | 0.83 | MAOB (0.54) | TSPOPOLBKMT2AHPGDKDM4E | |
| SCHEMBL5702540 | 0.82 | TSPO (0.81) | TSPOMAPTTP53 | |
| SCHEMBL22082635 | 0.81 | TSPO (0.80) | TSPOPOLBMAPTTP53SMN1; SMN2 | |
| SCHEMBL7751594 | 0.77 | TSPO (0.50) | TSPOPOLBKMT2ATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |