Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.35 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.35 |
| ▸ | RPS17 | P08708 | 1/20 | 0.35 |
| ▸ | RPSA | P08865 | 1/20 | 0.35 |
| ▸ | RPS2 | P15880 | 1/20 | 0.35 |
| ▸ | RPL35A | P18077 | 1/20 | 0.35 |
| ▸ | RPL7 | P18124 | 1/20 | 0.35 |
| ▸ | RPL17 | P18621 | 1/20 | 0.35 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.35 |
| ▸ | RPS3 | P23396 | 1/20 | 0.35 |
| ▸ | RPS12 | P25398 | 1/20 | 0.35 |
| ▸ | RPL13 | P26373 | 1/20 | 0.35 |
| ▸ | RPL10 | P27635 | 1/20 | 0.35 |
| ▸ | RPL12 | P30050 | 1/20 | 0.35 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.35 |
| ▸ | RPL22 | P35268 | 1/20 | 0.35 |
| ▸ | RPL4 | P36578 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871033 | 0.89 | OPRD1 (0.44) | OPRD1OPRM1KMT2AKCNH2SLC6A2 | |
| SCHEMBL7503837 | 0.89 | OPRD1 (0.44) | OPRD1OPRM1KMT2AKCNH2SLC6A2 | |
| SCHEMBL7498243 | 0.89 | OPRD1 (0.44) | OPRD1OPRM1KMT2AKCNH2SLC6A2 | |
| SCHEMBL7497373 | 0.85 | SLC6A2 (0.41) | OPRM1KMT2AKCNH2SLC6A2SLC6A4 | |
| SCHEMBL7492223 | 0.83 | HTT (0.39) | OPRD1OPRM1KMT2AKCNH2SLC6A2 | |
| SCHEMBL5870866 | 0.83 | OPRM1 (0.41) | OPRD1OPRM1KCNH2SLC6A2SLC6A4 | |
| SCHEMBL7501264 | 0.83 | OPRD1 (0.42) | OPRD1OPRM1KMT2AKCNH2SLC6A3 | |
| SCHEMBL6499006 | 0.82 | EPHX2 (0.36) | OPRD1OPRM1KMT2ABRD4CREBBP | |
| SCHEMBL5871117 | 0.82 | OPRD1 (0.42) | OPRD1OPRM1KCNH2SLC6A3 | |
| SCHEMBL5870992 | 0.80 | OPRD1 (0.39) | OPRD1OPRM1KCNH2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
| EP-1187810-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001092226-A1 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHOD OF USE THEREOF | SEPRACOR, INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| WO-2000071518-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND THEIR USE | SEPRACOR, INC. (US) | 2000-11-30 | — | — | WO | disclosed |