Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326337 | 0.90 | POLB (0.49) | MAOAMAOBGAAKMT2AMEN1 | |
| SCHEMBL8329547 | 0.90 | CCR3 (0.47) | MAOAMAOBKMT2AMEN1POLB | |
| SCHEMBL8327678 | 0.89 | KMT2A (0.53) | MAOAMAOBKMT2AMEN1POLB | |
| SCHEMBL8324361 | 0.88 | CYP1A2 (0.40) | MAOAMAOBKMT2AMEN1POLB | |
| SCHEMBL8330452 | 0.88 | ALDH1A1 (0.43) | MAOAMAOBKMT2AMEN1POLB | |
| SCHEMBL8330708 | 0.86 | KMT2A (0.52) | LTA4HGAAKMT2AMEN1POLB | |
| SCHEMBL8329017 | 0.84 | ALDH1A1 (0.54) | MAOAMAOBGAAKMT2AMEN1 | |
| SCHEMBL7498335 | 0.80 | DRD4 (0.52) | CYP2D6 | |
| SCHEMBL8326116 | 0.76 | SLC6A4 (0.47) | — | |
| SCHEMBL8326146 | 0.75 | TP53 (0.48) | LTA4HGAAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |