Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495777 | 0.92 | HIF1A (0.44) | HIF1APTGS2 | |
| SCHEMBL17949971 | 0.87 | HIF1A (0.45) | HIF1APTGS2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7492706 | 0.87 | HIF1A (0.42) | HIF1APPARGPPARA | |
| SCHEMBL8544633 | 0.87 | HIF1A (0.44) | HIF1APPARG | |
| SCHEMBL7716053 | 0.83 | HIF1A (0.48) | HIF1APTGS2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7716055 | 0.83 | HIF1A (0.48) | HIF1APTGS2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17937973 | 0.83 | HIF1A (0.48) | HIF1APTGS2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7469941 | 0.83 | ALDH1A1 (0.35) | HIF1AFFAR1SLC6A4HTR2AKCNH2 | |
| SCHEMBL7469944 | 0.83 | ALDH1A1 (0.35) | HIF1AFFAR1SLC6A4HTR2AKCNH2 | |
| SCHEMBL7494032 | 0.82 | HIF1A (0.47) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207152-A2 | Pesticides | Bayer Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |