Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743258 | 0.76 | POLB (0.44) | POLBTSHRALDH1A1NPSR1MAPT | |
| SCHEMBL6940594 | 0.74 | HDAC4 (0.45) | HDAC4HDAC6HDAC3HDAC1POLB | |
| SCHEMBL7549400 | 0.73 | CES2 (0.37) | CA1CA2 | |
| SCHEMBL8111567 | 0.73 | TDP1 (0.36) | HDAC4HDAC6HDAC3HDAC1TSHR | |
| SCHEMBL6190130 | 0.73 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL15226462 | 0.71 | EPHX2 (0.42) | POLBTSHRALDH1A1NPSR1MAPT | |
| SCHEMBL7593446 | 0.71 | TSHR (0.44) | HDAC4HDAC6HDAC3HDAC1TSHR | |
| SCHEMBL2001481 | 0.70 | TSHR (0.52) | POLBTSHRALDH1A1L3MBTL1MTOR | |
| SCHEMBL17391075 | 0.70 | ALDH1A1 (0.48) | POLBALDH1A1L3MBTL1MAPT | |
| SCHEMBL11365723 | 0.69 | CNR2 (0.37) | POLBTSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834513-B1 | Pentafluorophenylazolopyrimidines | BASF AG (DE) | 2002-07-24 | — | — | EP | disclosed |
| US-5965561-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| US-5817663-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0834513-A2 | Pentafluorophenylazolopyrimidines | American Cyanamid Company (US) | 1998-04-08 | — | — | EP | disclosed |