Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 6/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.56 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504617 | 0.88 | HTR1A (0.60) | ACP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3110765 | 0.86 | EGFR (0.64) | ACP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL30307419 | 0.86 | EGFR (0.64) | ACP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7503774 | 0.85 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BHRH3 | |
| SCHEMBL7505829 | 0.85 | HTR1A (0.72) | ACP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7502035 | 0.84 | HTR1A (0.75) | HTR1AADRA1DADRA1AADRA1BHRH3 | |
| SCHEMBL7501930 | 0.84 | HTR1A (0.66) | ACP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7505406 | 0.84 | HTR1A (0.67) | ACP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7501744 | 0.83 | CYP1A2 (0.65) | HTR1AADRA1DADRA1AADRA1BHRH3 | |
| SCHEMBL7505432 | 0.82 | CCNC (0.71) | HTR1AADRA1DADRA1AADRA1BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |