Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.66 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.66 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | ACP1 | P24666 | 6/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501744 | 0.87 | CYP1A2 (0.65) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL7509008 | 0.86 | HTR1A (0.60) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL7499031 | 0.84 | ACP1 (0.63) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL7500994 | 0.84 | CYP1A2 (0.63) | FERMT2MAPTHTTRAB9AKDM4E | |
| SCHEMBL7505406 | 0.81 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL23202952 | 0.78 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL30827851 | 0.78 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL7505625 | 0.77 | HTR1A (0.69) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL7509385 | 0.77 | CYP1A2 (0.65) | HTR1AADRA1DADRA1AADRA1BFERMT2 | |
| SCHEMBL23202871 | 0.77 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BFERMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |