Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502141 | 1.00 | HSP90AA1 (0.60) | HSP90AA1MAPTBCHECYP2C19GUSB | |
| SCHEMBL7495298 | 0.84 | KMT2A (0.55) | HSP90AA1MAPTKDM4EMAOBMAOA | |
| SCHEMBL7501158 | 0.84 | GPR52 (0.43) | HSP90AA1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL7504812 | 0.84 | MAPT (0.55) | HSP90AA1MAPTBCHECYP2C19GUSB | |
| SCHEMBL7504814 | 0.84 | MAPT (0.55) | HSP90AA1MAPTBCHECYP2C19GUSB | |
| SCHEMBL7501148 | 0.84 | GPR52 (0.43) | HSP90AA1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL7495307 | 0.84 | KMT2A (0.55) | HSP90AA1MAPTKDM4EMAOBMAOA | |
| SCHEMBL7502617 | 0.83 | ACMSD (0.48) | HSP90AA1MAPTGUSBKDM4EMAOB | |
| SCHEMBL7502623 | 0.83 | ACMSD (0.48) | HSP90AA1MAPTGUSBKDM4EMAOB | |
| SCHEMBL7502579 | 0.83 | CHRNA7 (0.56) | MAPTGUSBKDM4EKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |