Sugi Predict

Sugi Predict / Compounds / SCHEMBL749958

SCHEMBL749958

SCHEMBL749958

COC(=O)NCNC(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.48
▸ TSHR P16473 6/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ HSD17B10 Q99714 1/20 0.36
▸ MGAM O43451 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ SI P14410 1/20 0.36
▸ MGAM2 Q2M2H8 1/20 0.36
▸ MAPK1 P28482 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ TET2 Q6N021 1/20 0.35
▸ EGLN1 Q9GZT9 1/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.33
▸ KEAP1 Q14145 1/20 0.33
▸ NFE2L2 Q16236 1/20 0.33
▸ HCAR2 Q8TDS4 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14591249 0.91 EPHX1 (0.43) EPHX1TSHRALDH1A1HSD17B10MGAM
SCHEMBL12743892 0.89 EPHX1 (0.41) EPHX1TSHRALDH1A1MGAMGAA
SCHEMBL13156111 0.89 EPHX1 (0.41) EPHX1TSHRALDH1A1HSD17B10MGAM
SCHEMBL15293386 0.87 EPHX1 (0.40) EPHX1TSHRALDH1A1SMN1; SMN2
SCHEMBL13010591 0.84 GAA (0.44) EPHX1TSHRALDH1A1HSD17B10MGAM
SCHEMBL12688267 0.84 EPHX1 (0.39) EPHX1TSHRHSD17B10MAPK1KEAP1
SCHEMBL17758505 0.83 EPHX1 (0.38) EPHX1TSHR
SCHEMBL13010535 0.83 ACHE (0.38) EPHX1TSHR
SCHEMBL14003421 0.83 ACHE (0.48) EPHX1
SCHEMBL14039346 0.83 SMN1; SMN2 (0.39) EPHX1TSHRGAAMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5206412-A Reacting alkylphenylcarbamate with methylene bis(alkyl carbamate); acid catlayst ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-04-27 — — US claimed
US-11837750-B2 Lithium ion battery using crosslinkable separator ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-12-05 — — US disclosed
WO-2022167637-A1 PROCESS FOR MODIFYING AN AROMATIC POLYETHER BACKBONE AND A MODIFIED POLYETHER OBTAINED BY THIS PROCESS Technische Universität Berlin (DE) 2022-08-11 — — WO disclosed
EP-3739392-A1 DEVELOPING ROLLER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-11-18 — — EP disclosed
US-20180079850-A1 NON-AQUEOUS CROSS-LINKABLE FLUOROPOLYMER COMPOSITIONS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2018-03-22 — — US disclosed
US-20170254927-A1 HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS ALCON INC. (CH) 2017-09-07 — — US disclosed
US-20170235224-A1 PHOTOSENSITIVE RESIN COMPOSITION, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT THEREOF CHI MEI CORPORATION (TW) 2017-08-17 — — US disclosed
US-9684095-B2 Hydrophilized carbosiloxane vinylic monomers NOVARTIS AG (CH) 2017-06-20 — — US disclosed
US-9683151-B2 Non-aqueous fluoropolymer compositions SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2017-06-20 — — US disclosed
US-9671687-B2 Coloring composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, and image display device FUJIFILM CORPORATION (JP) 2017-06-06 — — US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 — — US disclosed
US-7282555-B2 Method for incorporating nitrogen containing methine light absorbers in pet and compositions thereof EASTMAN CHEMICAL COMPANY (US) 2007-10-16 — — US disclosed
US-20070212623-A1 Dye-containing negative working curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2007-09-13 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070190435-A1 Dye-containing photosensitive composition, color filter using the same, and production method thereof FUJIFILM CORPORATION (JP) 2007-08-16 — — US disclosed
US-20070099096-A1 Dye-containing curable composition, color filter and method of producing thereof FUJIFILM CORPORATION 2007-05-03 — — US disclosed
US-20070072096-A1 Negative curable dye-containing composition, color filter, and method of manufacturing the same FUJI PHOTO FILM CO., LTD. 2007-03-29 — — US disclosed
US-5220061-A Slowyly mixing n,n dialkyl-n-phenylurea and methylene bis/ alkyl carbamate/ with acid catalyst; heating ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-06-15 — — US disclosed
US-5206412-A Reacting alkylphenylcarbamate with methylene bis(alkyl carbamate); acid catlayst ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-04-27 — — US disclosed
US-5126476-A Reaction of aromatic compound with alkylenebis(alkyl carbamate) in presence of acid catalyst and polar aprotic solv ent ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170254927-A1 HYDROPHILIZED CARBOSILOXANE VINYLIC MONOMERS VCL, MACF1, HCAR1 EPHX1 180/4885TSHR 3251/4885ALDH1A1 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.