Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.61 |
| ▸ | RELA | Q04206 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320339 | 0.78 | KDM4E (0.39) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL2519357 | 0.77 | KDM4E (0.53) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL19748096 | 0.77 | KDM4E (0.57) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL24517982 | 0.77 | KDM4E (0.43) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL4779545 | 0.76 | RAB9A (1.00) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL4798554 | 0.73 | NPC1 (1.00) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL23808124 | 0.73 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL25495621 | 0.73 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL9090176 | 0.72 | KDM4E (0.47) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL14006807 | 0.69 | NPC1 (0.40) | ALDH1A1MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773946-B1 | IMIDAZOPYRIDINE-AZOLIDINONES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6124313-A | ACTIVE DRUG FOR TREATING GASTRO-INTESTINAL AILMENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-09-26 | — | — | US | disclosed |
| EP-0773946-A1 | IMIDAZOPYRIDINE-AZOLIDINONES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-21 | — | — | EP | disclosed |
| EP-0773945-A1 | ACYL IMIDAZOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003404-A1 | ACYL IMIDAZOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-08 | — | — | WO | disclosed |
| WO-1996003405-A1 | IMIDAZOPYRIDINE-AZOLIDINONES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-08 | — | — | WO | disclosed |