Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230681 | 0.90 | CACNA1B (0.43) | CACNA1BHRH1CCR3ACACBHRH2 | |
| SCHEMBL5229426 | 0.89 | CACNA1B (0.44) | CACNA1BHRH1CCR3KCNA5ACACB | |
| SCHEMBL14431864 | 0.86 | SIGMAR1 (0.34) | CACNA1BCCR3SIGMAR1RAB9A | |
| SCHEMBL14432572 | 0.84 | KCNA5 (0.43) | CACNA1BHRH1CCR3KCNA5ACACB | |
| SCHEMBL5242024 | 0.83 | CACNA1B (0.42) | CACNA1BHRH1CCR3DRD2DRD3 | |
| SCHEMBL5241749 | 0.82 | CACNA1B (0.48) | CACNA1BHRH1KCNA5DRD2DRD3 | |
| SCHEMBL14431932 | 0.82 | L3MBTL1 (0.45) | CACNA1BHRH1CCR3MEN1KMT2A | |
| SCHEMBL5240611 | 0.81 | CACNA1B (0.33) | CACNA1BCCR3SIGMAR1 | |
| SCHEMBL5243213 | 0.81 | LMNA (0.50) | CACNA1BMEN1KMT2A | |
| SCHEMBL5235391 | 0.81 | CACNA1B (0.41) | CACNA1BDRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254895-A1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |