Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055837 | 0.88 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2BACE1 | |
| SCHEMBL29365331 | 0.88 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2BACE1 | |
| SCHEMBL82266 | 0.88 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2BACE1 | |
| SCHEMBL82267 | 0.88 | NFKB1 (0.77) | NFKB1MAOBP4HBABCG2BACE1 | |
| Hydrochloric Acid SCHEMBL6821798 | 0.86 | NFKB1 (0.74) | NFKB1MAOBP4HBABCG2BACE1 | |
| SCHEMBL1150939 | 0.86 | PTGER3 (0.63) | NFKB1PTGER3PTGER2PTGER4MAPT | |
| SCHEMBL3214322 | 0.86 | PTGER3 (0.63) | NFKB1PTGER3PTGER2PTGER4MAPT | |
| SCHEMBL309761 | 0.86 | PTGER3 (0.63) | NFKB1PTGER3PTGER2PTGER4MAPT | |
| SCHEMBL7499891 | 0.84 | BACE1 (0.60) | NFKB1MAOBP4HBABCG2BACE1 | |
| SCHEMBL9518819 | 0.81 | NFKB1 (0.50) | NFKB1MAOBP4HBABCG2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218337-A4 | SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INST (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1218337-A1 | SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019783-A1 | SYNTHESIS OF [3,5,7]-1H-IMIDAZO[1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 2001-03-22 | — | — | WO | disclosed |