SCHEMBL749991

SCHEMBL749991

CCC1COC(c2ccccc2)(c2ccccc2CO)O1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 17/20 0.43
ADRA1B P35368 14/20 0.43
HTR1A P08908 13/20 0.43
ADRA1D P25100 12/20 0.43
GAA P10253 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749621 0.91 ADRA1A (0.42) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL748670 0.90 HTR1A (0.43) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL752340 0.89 ADRA1A (0.42) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL750279 0.88 HTR1A (0.41) ADRA1AADRA1BHTR1AADRA1D
SCHEMBL3412898 0.88 ADRA1A (0.43) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL750523 0.88 ADRA1A (0.41) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL748991 0.87 ADRA1A (0.41) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL4323822 0.86 ADRA1A (0.42) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL750050 0.85 ADRA1A (0.37) ADRA1AADRA1BHTR1AADRA1DGAA
SCHEMBL749307 0.85 ADRA1A (0.41) ADRA1AADRA1BHTR1AADRA1DGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US claimed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed