Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500221 | 0.90 | ITGB3 (0.46) | ITGB3ITGA2BKMT2AMEN1CYP11B1 | |
| SCHEMBL8009746 | 0.90 | ITGB3 (0.45) | ITGB3ITGA2BKMT2AMEN1CYP11B1 | |
| SCHEMBL8180044 | 0.77 | ITGB3 (0.51) | ITGB3ITGA2BKMT2AMEN1LTB4R | |
| SCHEMBL7798164 | 0.73 | ITGB3 (0.61) | ITGB3ITGA2BKMT2AMEN1LTB4R | |
| SCHEMBL8363349 | 0.73 | ITGB3 (0.61) | ITGB3ITGA2BKMT2AMEN1LTB4R | |
| SCHEMBL7795113 | 0.72 | ITGB3 (0.55) | ITGB3ITGA2BKMT2AMEN1LTB4R | |
| Hydrochloric Acid SCHEMBL7798200 | 0.72 | ITGB3 (0.60) | ITGB3ITGA2BKMT2AMEN1LTB4R | |
| SCHEMBL8381416 | 0.71 | ITGB3 (1.00) | ITGB3ITGA2BKMT2AMEN1LTB4R | |
| Trifluoroacetic Acid SCHEMBL8558440 | 0.71 | ITGB3 (0.62) | ITGB3ITGA2BKMT2AMEN1PTGDR2 | |
| SCHEMBL8379555 | 0.70 | ITGB3 (0.71) | ITGB3ITGA2BKMT2AMEN1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | claimed |
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |