Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500221 | 0.96 | ITGB3 (0.46) | ITGB3ITGA2BCNR2CTNNB1WNT3A | |
| SCHEMBL7499998 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BCNR2CTNNB1WNT3A | |
| SCHEMBL7363023 | 0.74 | ITGB3 (0.49) | ITGB3ITGA2BL3MBTL1ALDH1A1LMNA | |
| SCHEMBL7368949 | 0.73 | ITGB3 (0.50) | ITGB3ITGA2BALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7358969 | 0.71 | KMT2A (0.67) | L3MBTL1CYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL7407172 | 0.70 | KMT2A (0.50) | ITGB3ITGA2BL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8012315 | 0.69 | ITGB3 (0.52) | ITGB3ITGA2BL3MBTL1ALDH1A1LMNA | |
| SCHEMBL8180044 | 0.69 | ITGB3 (0.51) | ITGB3ITGA2BL3MBTL1KMT2AMEN1 | |
| SCHEMBL8641278 | 0.69 | NPSR1 (0.36) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8633992 | 0.68 | ALDH1A1 (0.55) | CYP3A4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |