Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009746 | 0.96 | ITGB3 (0.45) | ITGB3ITGA2BCNR2MEN1KMT2A | |
| SCHEMBL7499998 | 0.90 | ITGB3 (0.55) | ITGB3ITGA2BCNR2MEN1KMT2A | |
| SCHEMBL7368949 | 0.72 | ITGB3 (0.50) | ITGB3ITGA2BMEN1KMT2AALDH1A1 | |
| SCHEMBL7363023 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BMEN1KMT2AL3MBTL1 | |
| SCHEMBL8180044 | 0.70 | ITGB3 (0.51) | ITGB3ITGA2BMEN1KMT2AL3MBTL1 | |
| SCHEMBL7358969 | 0.68 | KMT2A (0.67) | MEN1KMT2AL3MBTL1CYP3A4CYP2C9 | |
| SCHEMBL7407172 | 0.67 | KMT2A (0.50) | ITGB3ITGA2BMEN1KMT2AL3MBTL1 | |
| SCHEMBL8012315 | 0.67 | ITGB3 (0.52) | ITGB3ITGA2BMEN1KMT2AL3MBTL1 | |
| SCHEMBL8641278 | 0.66 | NPSR1 (0.36) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8633992 | 0.65 | ALDH1A1 (0.55) | MEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |