Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485902 | 0.90 | LMNA (0.37) | LMNAKMT2AMEN1HTTPOLB | |
| SCHEMBL2222860 | 0.90 | LMNA (0.34) | LMNAKMT2AMEN1 | |
| SCHEMBL27573128 | 0.74 | TDP1 (0.34) | LMNAKMT2AMEN1 | |
| SCHEMBL9908382 | 0.70 | CA12 (0.37) | KMT2AMEN1POLB | |
| SCHEMBL6477427 | 0.69 | LOXL2 (0.33) | LMNAKMT2AMEN1 | |
| SCHEMBL4378015 | 0.69 | MEN1 (0.36) | LMNAKMT2AMEN1POLB | |
| Hydrochloric Acid SCHEMBL6526925 | 0.67 | KDM4E (0.33) | LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL22468715 | 0.67 | MEN1 (0.35) | LMNAKMT2AMEN1 | |
| SCHEMBL6599401 | 0.65 | KDM4E (0.38) | KMT2AMEN1HTTPOLBTHRB | |
| SCHEMBL14451743 | 0.65 | LMNA (0.38) | LMNAKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |