SCHEMBL7500157

SCHEMBL7500157

CC(C)(C)CC(=O)OC(=O)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.37
LMNA P02545 1/20 0.33
ELANE P08246 2/20 0.32
PRKCA P17252 1/20 0.32
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL385886 0.84 ALDH1A1 (0.41) MIFLMNANPC1TP53RAB9A
SCHEMBL20788529 0.79 HMGCR (0.31)
SCHEMBL6567119 0.79 MIF (0.31) MIFLMNA
SCHEMBL6564743 0.79 MIF (0.31) MIFLMNA
SCHEMBL3760885 0.79 ALDH1A1 (0.31) MIFLMNA
SCHEMBL779254 0.79 ALDH1A1 (0.38) ELANEPRKCASMN1; SMN2
SCHEMBL2182293 0.77 ALDH1A1 (0.45) MIFLMNANPC1TP53RAB9A
SCHEMBL29228022 0.77 PRKCA (0.38) ELANEPRKCA
SCHEMBL182236 0.77 ALDH1A1 (0.42) MIFLMNANPC1TP53RAB9A
SCHEMBL7905388 0.75 MIF (0.33) MIFLMNANPC1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2763676-B2 1998-06-11 JP claimed
EP-0376859-B1 METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES EASTMAN KODAK COMPANY (US) 1993-03-31 EP claimed
EP-0448602-A1 METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES EASTMAN KODAK COMPANY (US) 1991-10-02 EP claimed
US-5051529-A Transesterification, amidation and acetoacetylation of amines, alcohols, mercaptans and polymers EASTMAN KODAK COMPANY (US) 1991-09-24 US claimed
EP-0376859-A1 Method for functionalization of nucleophiles EASTMAN KODAK COMPANY (US) 1990-07-04 EP claimed
WO-1990006911-A1 METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES EASTMAN KODAK COMPANY (US) 1990-06-28 WO claimed
EP-1218337-A4 SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS TORREY PINES INST (US) 2002-09-11 EP disclosed
EP-1218337-A1 SYNTHESIS OF 3,5,7]-1H-IMIDAZO 1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 2002-07-03 EP disclosed
WO-2001019783-A1 SYNTHESIS OF [3,5,7]-1H-IMIDAZO[1,5-A]IMIDAZOL-2(3H)-ONE COMPOUNDS TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 2001-03-22 WO disclosed
US-5206419-A Curing agents, coatings EASTMAN KODAK COMPANY (US) 1993-04-27 US disclosed
EP-0376859-B1 METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES EASTMAN KODAK COMPANY (US) 1993-03-31 EP disclosed
US-5113011-A Acetoacetylation EASTMAN KODAK COMPANY (US) 1992-05-12 US disclosed
EP-0448602-A1 METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES EASTMAN KODAK COMPANY (US) 1991-10-02 EP disclosed
US-5051529-A Transesterification, amidation and acetoacetylation of amines, alcohols, mercaptans and polymers EASTMAN KODAK COMPANY (US) 1991-09-24 US disclosed
EP-0376859-A1 Method for functionalization of nucleophiles EASTMAN KODAK COMPANY (US) 1990-07-04 EP disclosed
WO-1990006911-A1 METHOD FOR FUNCTIONALIZATION OF NUCLEOPHILES EASTMAN KODAK COMPANY (US) 1990-06-28 WO disclosed