Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385886 | 0.84 | ALDH1A1 (0.41) | MIFLMNAALDH1A1NPC1TP53 | |
| SCHEMBL28224137 | 0.78 | ALDH1A1 (0.33) | MIFLMNAALDH1A1 | |
| SCHEMBL182236 | 0.77 | ALDH1A1 (0.42) | MIFLMNAALDH1A1NPC1TP53 | |
| SCHEMBL27475793 | 0.77 | HMGCR (0.36) | MIFLMNAALDH1A1NPC1TP53 | |
| SCHEMBL2182293 | 0.77 | ALDH1A1 (0.45) | MIFLMNAALDH1A1NPC1TP53 | |
| SCHEMBL394513 | 0.76 | LMNA (0.36) | MIFLMNAALDH1A1 | |
| SCHEMBL4644724 | 0.75 | CYP2D6 (0.33) | MIFLMNANPC1TP53RAB9A | |
| SCHEMBL7500157 | 0.75 | MIF (0.37) | MIFLMNANPC1TP53RAB9A | |
| SCHEMBL26334814 | 0.75 | LMNA (0.40) | MIFLMNANPC1TP53RAB9A | |
| SCHEMBL6564743 | 0.75 | MIF (0.31) | MIFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194438-B1 | ANTITUMOR AGENTS; ANTICANCER AGENTS; FARNESYL-PROTEIN TRANSFERASE INHIBITOR | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-1006113-A1 | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use to inhibit abnormal cell growth | Pfizer Products Inc. (US) | 2000-06-07 | — | — | EP | disclosed |