Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA7 | P43166 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648388 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 | |
| SCHEMBL24484518 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL6673635 | 0.82 | HPGD (0.56) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL6653339 | 0.78 | SRD5A1 (0.44) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL21855441 | 0.75 | CDC7 (0.42) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL4971253 | 0.74 | HPGD (0.50) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL606972 | 0.72 | PPARG (0.50) | ALDH1A1HPGDKDM4ETDP1LMNA | |
| SCHEMBL17918272 | 0.71 | METAP1 (0.44) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 | |
| SCHEMBL6648373 | 0.70 | L3MBTL1 (0.42) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 | |
| SCHEMBL1625402 | 0.69 | SPR (0.46) | ALDH1A1HPGDKDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535034-B1 | PHARMACEUTICALLY ACTIVE BENZOQUINAZOLINE COMPOUNDS | WELLCOME FOUND (GB) | 2002-08-14 | — | — | EP | disclosed |