SCHEMBL7500247

SCHEMBL7500247

CNC(=O)C(=NOC)c1ccccc1C(C)ON=CC(=NOC)c1ccc(C)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7498643 0.91 ALDH1A1 (0.34)
SCHEMBL7492778 0.91 HIF1A (0.36)
SCHEMBL7504773 0.89 LMNA (0.36)
SCHEMBL7542494 0.88 NPC1 (0.30)
SCHEMBL7545134 0.87 KAT6A (0.34)
SCHEMBL6704054 0.83 HIF1A (0.36)
SCHEMBL7504420 0.82 HIF1A (0.38)
SCHEMBL7501826 0.82 HIF1A (0.34)
SCHEMBL7784487 0.81 RECQL (0.32)
SCHEMBL8615822 0.81 MAPK14 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed
EP-0865424-A1 PESTICIDES Novartis AG (CH) 1998-09-23 EP disclosed
WO-1997020809-A1 PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed