Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 16/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 16/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 16/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 16/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | GABRP | O00591 | 5/20 | 0.42 |
| ▸ | GABRD | O14764 | 5/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.42 |
| ▸ | GABRE | P78334 | 5/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503968 | 0.90 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7495314 | 0.85 | MTNR1A (0.43) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8182812 | 0.83 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7495932 | 0.83 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7494361 | 0.81 | ALDH1A1 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9838495 | 0.80 | GABRA1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9536372 | 0.79 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9536364 | 0.79 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9534768 | 0.79 | GABRA1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7496617 | 0.77 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820454-B1 | ANELLATED BETA-CARBOLINES | SCHERING AG (DE) | 2002-07-24 | — | — | EP | disclosed |