Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.68 |
| ▸ | HTR2A | P28223 | 11/20 | 0.68 |
| ▸ | HTR2C | P28335 | 11/20 | 0.68 |
| ▸ | HTR2B | P41595 | 11/20 | 0.68 |
| ▸ | DRD2 | P14416 | 11/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778970 | 0.98 | SIGMAR1 (0.70) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL18494688 | 0.94 | SIGMAR1 (0.70) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL18494326 | 0.90 | SIGMAR1 (0.74) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7943845 | 0.83 | SIGMAR1 (0.65) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL30303547 | 0.83 | ALDH1A1 (0.57) | SIGMAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL1912704 | 0.82 | SIGMAR1 (0.64) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL29790999 | 0.82 | SIGMAR1 (0.64) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL15692839 | 0.81 | ALDH1A1 (0.54) | SIGMAR1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL6836356 | 0.81 | SIGMAR1 (1.00) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL3497387 | 0.80 | SIGMAR1 (0.54) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597423-B1 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-6011150-A | SYNTHETIC INTERMEDIATE OF A 1 BETA-METHYLCARBAPENEM DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| US-5631363-A | ANTIBIOTIC INTERMEDIATE | TANABE SEIYAKU CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5442055-A | Chemical intermediates for carbapenicillins | TANABE SEIYAKU CO., LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0597423-A2 | Azetidinone compound and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |