Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15017182 | 0.59 | GPR35 (0.32) | — | |
| SCHEMBL1938532 | 0.57 | — | — | |
| SCHEMBL3317399 | 0.55 | — | — | |
| SCHEMBL630410 | 0.54 | — | — | |
| SCHEMBL31711469 | 0.51 | ABCC8 (0.39) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL14953642 | 0.51 | — | — | |
| SCHEMBL9778209 | 0.47 | — | — | |
| SCHEMBL11163671 | 0.47 | — | — | |
| SCHEMBL18311461 | 0.46 | TDP1 (0.56) | ALDH1A1CYP3A4HPGDTSHRHIF1A | |
| SCHEMBL7513494 | 0.46 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRHIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112073-A4 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-10-25 | — | — | EP | disclosed |
| EP-1112073-A1 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000009132-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |