Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581891 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL753289 | 0.84 | KEAP1 (0.46) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL15962070 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL8786682 | 0.81 | CES2 (0.42) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL31439012 | 0.80 | CFTR (0.56) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL18113432 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL600522 | 0.78 | KEAP1 (0.55) | KDM4EALDH1A1HPGDHSD17B10KEAP1 | |
| SCHEMBL29625095 | 0.78 | NOTUM (0.44) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL24276000 | 0.78 | NOTUM (0.44) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL29625097 | 0.78 | NOTUM (0.44) | KDM4EALDH1A1HPGDHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100395244-C | Quinolone carboxylic acid derivatives or their salts | TOYAMA CHEMICAL CO LTD (JP) | 2008-06-18 | — | — | CN | disclosed |
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6025370-A | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0882725-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |