Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501966 | 0.85 | HTR1A (0.46) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7510365 | 0.80 | HTR1A (0.65) | ALDH1A1SMN1; SMN2KDM4EHTTHTR1A | |
| SCHEMBL7507351 | 0.79 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7504935 | 0.79 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7505071 | 0.77 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7509556 | 0.77 | MAPK14 (0.42) | ALDH1A1SMN1; SMN2KDM4EHTTHTR1A | |
| SCHEMBL7508998 | 0.75 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7507682 | 0.75 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7502757 | 0.75 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 | |
| SCHEMBL7506346 | 0.73 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2KDM4EHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |