Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500694 | 0.81 | TAAR1 (0.39) | RIPK1CES2CES1 | |
| SCHEMBL81560 | 0.78 | SIRT2 (0.34) | RIPK1CES2CES1CA2 | |
| SCHEMBL21399635 | 0.78 | TYR (0.47) | RIPK1 | |
| SCHEMBL81621 | 0.78 | CA2 (0.46) | RIPK1CES2CES1CA2 | |
| SCHEMBL146632 | 0.77 | RIPK1 (0.36) | RIPK1CES2CES1CA2 | |
| SCHEMBL6130282 | 0.76 | FFAR4 (0.31) | — | |
| SCHEMBL6965983 | 0.75 | TAAR1 (0.50) | — | |
| SCHEMBL3237766 | 0.74 | RIPK1 (0.33) | RIPK1CES2CES1CA2 | |
| SCHEMBL1241765 | 0.73 | CES2 (0.38) | RIPK1CES2CES1CA2 | |
| SCHEMBL16404703 | 0.73 | RIPK1 (0.34) | RIPK1CES2CES1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |