Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | STK3 | Q13188 | 2/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.45 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503788 | 0.90 | KDM4E (0.52) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7507131 | 0.89 | SMN1; SMN2 (0.53) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7504497 | 0.85 | LMNA (0.56) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7510138 | 0.84 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7512679 | 0.84 | CYP1A2 (0.51) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL23202861 | 0.82 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7505544 | 0.82 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7504942 | 0.82 | HPGD (0.50) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7509990 | 0.82 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BPRKD3 | |
| SCHEMBL7511143 | 0.82 | RPS6KB1 (0.50) | HTR1AADRA1DADRA1AADRA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |