Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504497 | 0.84 | LMNA (0.56) | ADORA2AADORA1HTR1AADRA1DADRA1A | |
| SCHEMBL7501246 | 0.84 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BRAB9A | |
| SCHEMBL7504942 | 0.81 | HPGD (0.50) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL7509990 | 0.81 | HTR1A (0.47) | ADORA2AADORA1HTR1AADRA1DADRA1A | |
| SCHEMBL7510138 | 0.81 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BRAB9A | |
| SCHEMBL7503084 | 0.80 | KDM4E (0.48) | ADORA2AADORA1HTR1AADRA1DADRA1A | |
| SCHEMBL7509308 | 0.80 | SMN1; SMN2 (0.51) | CYP1A2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7507131 | 0.80 | SMN1; SMN2 (0.53) | CYP1A2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL23202861 | 0.78 | HTR1A (0.47) | ADORA2AADORA1HTR1AADRA1DADRA1A | |
| SCHEMBL7505544 | 0.78 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |