Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31773 | 0.66 | LOXL2 (0.52) | LOXL2ABHD6CYP4F2CYP4A11RAB9A | |
| SCHEMBL20209837 | 0.66 | CYP2D6 (0.62) | LOXL2ABHD6CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL1373046 | 0.66 | CYP2D6 (0.67) | LOXL2ABHD6CYP4F2CYP4A11NPC1 | |
| SCHEMBL9236088 | 0.66 | LOXL2 (0.49) | LOXL2CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL1512308 | 0.66 | CHRM3 (0.72) | LOXL2CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| SCHEMBL7830882 | 0.66 | LOXL2 (0.62) | LOXL2ABHD6CYP4F2CYP4A11RAB9A | |
| SCHEMBL12563565 | 0.65 | CYP2D6 (0.69) | LOXL2CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL13848767 | 0.65 | LOXL2 (0.50) | LOXL2ABHD6CYP4F2CYP4A11CD74 | |
| SCHEMBL18938160 | 0.65 | ABHD6 (0.60) | LOXL2ABHD6CYP4F2CYP4A11RAB9A | |
| SCHEMBL22953708 | 0.65 | CD74 (0.52) | LOXL2ABHD6CYP4F2CYP4A11CD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0734386-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | Abbott Laboratories (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1995016687-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LABORATORIES (US) | 1995-06-22 | — | — | WO | disclosed |