Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501158 | 1.00 | GPR52 (0.43) | GPR52HSP90AA1NFE2L2ALDH1A1LMNA | |
| SCHEMBL7502141 | 0.84 | HSP90AA1 (0.60) | HSP90AA1ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL7502155 | 0.84 | HSP90AA1 (0.60) | HSP90AA1ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL20518208 | 0.83 | NFE2L2 (0.45) | HSP90AA1NFE2L2LMNAMAPTKMT2A | |
| SCHEMBL7495307 | 0.83 | KMT2A (0.55) | HSP90AA1ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7495298 | 0.83 | KMT2A (0.55) | HSP90AA1ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7504814 | 0.83 | MAPT (0.55) | HSP90AA1ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7504812 | 0.83 | MAPT (0.55) | HSP90AA1ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL7501717 | 0.82 | ABCG2 (0.59) | GPR52ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL7501712 | 0.82 | ABCG2 (0.59) | GPR52ALDH1A1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924202-B1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6071943-A | IMMUNOMODULATORS WHICH SUPPRESS SPECIFIC CYTOKINES, FOR AUTOIMMUNE DISEASES | SSP CO. LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0924202-A1 | Imidazole derivative and medicine comprising the same as active ingredient | SSP Co., Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |