Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500293 | 0.76 | ADH1B (0.30) | — | |
| SCHEMBL7496497 | 0.75 | TBXAS1 (0.30) | TBXAS1 | |
| SCHEMBL20671646 | 0.70 | RECQL (0.42) | RECQLCYP2C9CYP2C19 | |
| SCHEMBL7498371 | 0.68 | — | — | |
| SCHEMBL30107358 | 0.67 | POLB (0.53) | RECQLPOLBCYP2C9CYP2C19 | |
| SCHEMBL7496162 | 0.66 | CYP3A4 (0.34) | — | |
| SCHEMBL7496321 | 0.62 | IDO1 (0.40) | — | |
| SCHEMBL27824293 | 0.59 | RECQL (0.62) | RECQLPOLBCYP2C9CYP2C19 | |
| SCHEMBL21246171 | 0.59 | RECQL (0.53) | RECQLPOLBCYP2C9CYP2C19 | |
| SCHEMBL29884167 | 0.59 | RECQL (0.53) | RECQLPOLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760370-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5990101-A | Carbapenem derivatives | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0760370-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-03-05 | — | — | EP | disclosed |