Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064466 | 0.81 | HTR6 (0.47) | HTR6KDM2BHSD11B1 | |
| SCHEMBL7496870 | 0.78 | HTR6 (0.57) | HTR6LMNAKDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL7493087 | 0.78 | KDM2B (0.45) | HTR6KDM2BLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2064873 | 0.71 | HTR6 (0.47) | HTR6KDM2BHSD11B1KDM4EALDH1A1 | |
| SCHEMBL7005955 | 0.70 | HTR6 (0.49) | HTR6 | |
| SCHEMBL7005953 | 0.70 | HTR6 (0.49) | HTR6 | |
| SCHEMBL2065517 | 0.69 | HTR6 (0.46) | HTR6 | |
| SCHEMBL7499298 | 0.69 | HTR6 (0.47) | HTR6ALDH1A1PKM | |
| SCHEMBL2064304 | 0.68 | HTR6 (0.59) | HTR6 | |
| SCHEMBL7496649 | 0.67 | HTR6 (0.41) | HTR6KDM2BKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | disclosed |