Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064379 | 0.75 | HTR6 (0.77) | HTR6 | |
| SCHEMBL7501687 | 0.73 | HTR6 (0.45) | HTR6 | |
| SCHEMBL4733029 | 0.72 | HTR6 (0.46) | HTR6 | |
| SCHEMBL10551779 | 0.71 | HTR6 (0.40) | HTR6ALDH1A1CA12CA9CA2 | |
| SCHEMBL21147084 | 0.71 | ALDH1A1 (0.41) | HTR6ALDH1A1CA12CA9CA2 | |
| SCHEMBL10557200 | 0.71 | ALDH1A1 (0.41) | HTR6ALDH1A1CA12CA9CA2 | |
| SCHEMBL10552139 | 0.70 | PIK3C3 (0.48) | HTR6ALDH1A1CA12CA9CA2 | |
| SCHEMBL7867384 | 0.70 | HTR6 (0.59) | HTR6ALDH1A1PKMCA12CA9 | |
| SCHEMBL10553874 | 0.69 | RECQL (0.52) | HTR6ALDH1A1CA12CA9CA2 | |
| SCHEMBL30759205 | 0.69 | RECQL (0.46) | HTR6ALDH1A1CA12CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204662-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS Allelix Corp. (CA) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012629-A1 | AZAINDOLES HAVING SEROTONIN RECEPTOR AFFINITY | NPS ALLELIX CORP. (US) | 2001-02-22 | — | — | WO | disclosed |