Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.37 |
| ▸ | THRA | P10827 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629875 | 0.85 | MAPT (0.59) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL5529876 | 0.84 | LTA4H (0.48) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL16678909 | 0.82 | ALOX15 (0.39) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL29362698 | 0.82 | ALOX15 (0.39) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL29437870 | 0.80 | MAPT (0.43) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL3803700 | 0.79 | TDP1 (0.45) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL2461701 | 0.77 | ALOX15 (0.36) | ALOX15MAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL5381954 | 0.77 | HSPB1 (0.51) | MAPTMAPK1ALDH1A1MEN1LMNA | |
| SCHEMBL3842527 | 0.76 | MAPT (0.74) | MAPTALOX15MAPK1TDP1ALDH1A1 | |
| SCHEMBL391385 | 0.76 | MAPT (0.74) | MAPTALOX15MAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129081-B2 | Photoconductive imaging members | XEROX CORPORATION (US) | 2012-03-06 | — | — | US | claimed |
| US-20100068639-A1 | PHOTOCONDUCTIVE IMAGING MEMBERS | XEROX CORPORATION (US) | 2010-03-18 | — | — | US | claimed |
| US-8258503-B2 | Charge generation layer doped with dihalogen ether | XEROX CORPORATION (US) | 2012-09-04 | — | — | US | disclosed |
| US-8129081-B2 | Photoconductive imaging members | XEROX CORPORATION (US) | 2012-03-06 | — | — | US | disclosed |
| US-20100230661-A1 | CHARGE GENERATION LAYER DOPED WITH DIHALOGEN ETHER | XEROX CORPORATION (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100068639-A1 | PHOTOCONDUCTIVE IMAGING MEMBERS | XEROX CORPORATION (US) | 2010-03-18 | — | — | US | disclosed |