Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967140 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL27330745 | 0.86 | — | — | |
| SCHEMBL967805 | 0.81 | — | — | |
| SCHEMBL30786309 | 0.80 | EPHX1 (0.33) | ALOX5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28808760 | 0.79 | ALOX5 (0.40) | ALOX5HPGDTSHRALDH1A1 | |
| SCHEMBL967397 | 0.79 | FAAH (0.45) | ALOX5HPGDTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL27354002 | 0.78 | BRD4 (0.33) | ALOX5ALDH1A1DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL21906392 | 0.77 | FAAH (0.43) | ALOX5HPGDTSHRALDH1A1 | |
| SCHEMBL967457 | 0.77 | FAAH (0.48) | ALOX5HPGDTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL21906386 | 0.76 | FAAH (0.47) | ALOX5HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |